Hollywood is the entertainment capital of the world, and actors are at the forefront of the industry. However, like any profession, acting comes with its own set of risks and dangers. One of the most common causes of death among Hollywood actors is drug overdose. Drug addiction and substance abuse have long been a problem in the entertainment industry. Actors, like anyone else, may turn to drugs as a way to cope with the stress and pressure of their careers. However, the fast-paced and demanding nature of the industry can make it even more difficult for actors to overcome addiction. One of the most high-profile examples of drug overdose in Hollywood is the death of Heath Ledger. The Australian actor, known for his role as the Joker in "The Dark Knight," died in 2008 from an accidental overdose of prescription drugs. Ledger had been struggling with insomnia and had been taking a combination of sleeping pills and painkillers. Another notable example is the death of River Phoenix. The young actor, known for his roles in films such as "Stand by Me" and "My Own Private Idaho," died in 1993 from a drug overdose outside a Hollywood nightclub. Phoenix had been using a combination of cocaine and heroin. These are just a few examples of the many actors whose lives have been cut short due to drug overdose. Other notable cases include Chris Farley, Philip Seymour Hoffman, and Cory Monteith. Drug addiction is a serious issue that affects not only actors but also people from all walks of life. It is important for those in the entertainment industry, as well as society as a whole, to recognize the dangers of drug abuse and work toward prevention and treatment. It is not only the actors who are struggling with drug addiction, it is also the people around them. It is important for friends, family, and colleagues to be aware of the signs of addiction and to offer support and assistance. In conclusion, drug overdose is one of the most common causes of death among Hollywood actors. It is a serious issue that affects not only the actors themselves but also those around them. It is crucial for the entertainment industry and society as a whole to recognize the dangers of drug abuse and to work toward prevention and treatment. Dr. A. Arrazaghi. MD,FRCPC