False positive pregnancy test results in men are extremely rare and typically occur due to a variety of reasons. The most common cause of a false positive pregnancy test in men is due to a medical condition known as testicular feminization syndrome. This condition is characterized by the presence of female sex hormones, such as estrogen, in the male body. This can cause the production of certain hormones that can trigger a false positive pregnancy test. Another cause of false positive pregnancy test results in men is the presence of certain medications in the body. Some medications, such as antipsychotics, anti-anxiety, and anti-convulsant in addition to some antiparkinson drugs can cause a false positive pregnancy test result. Additionally, some herbal supplements and over-the-counter medications can also cause a false positive pregnancy test result. In rare cases, a false positive pregnancy test in men can also be caused by a tumor on the testicles or on the pituitary gland. These tumors can produce hormones that mimic pregnancy and trigger a false positive result on a pregnancy test. It is also possible for a false positive pregnancy test to occur due to a lab error or a faulty pregnancy test kit. This can happen if the test is not performed properly or if the test kit has been expired or damaged. It is important to note that a false positive pregnancy test result does not necessarily mean that a man is pregnant. It is important to follow up with a healthcare provider to determine the cause of the false positive result and to rule out any underlying medical conditions. In conclusion, a false positive pregnancy test in men is a rare occurrence and can be caused by a variety of reasons, including medical conditions such as testicular feminization syndrome, the presence of certain medications in the body, tumors on the testicles or pituitary gland, and lab errors or faulty test kits. If a man receives a false positive pregnancy test result, it is important to follow up with a healthcare provider to determine the cause of the result and rule out any underlying medical conditions. Dr. A. Arrazaghi. MD,FRCPC